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The principal cytochrome P450 isoenzyme involved seems to get CYP2E1, with CYP1A2 and CYP3A4 as added pathways. Around eighty five% of an oral dose seems while in the urine within just 24 hrs of administration, most since the glucuronide conjugate, with compact quantities of other conjugates and unchanged drug [see OVERDOSAGE] for toxicity informat